PHYSTAT 2011 Bayes and Discovery: Objective Bayesian Hypothesis Testing

نویسندگان

  • José M. Bernardo
  • J. M. Bernardo
چکیده

Let z be the available data which are assumed to have been generated as one random observation from model Mz = {p(z |ω),z ∈ Z,ω ∈ Ω}. Often, but not always, data will consist of a random sample z = {x1, . . . ,xn} from some distribution q(x |ω), with x ∈ X ; in this case p(z |ω) = Qn i=1 q(xi |ω) and Z = X . Let θ(ω) be the vector of interest. Without loss of generality, the model may explicitly be expressed in terms of θ so thatMz = {p(z |θ,λ),z ∈ Z,θ ∈ Θ,λ ∈ Λ}, where λ is some appropriately chosen nuisance parameter vector. Let π(θ,λ) = π(λ |θ)π(θ) be the assumed prior, and let π(θ |z) be the corresponding marginal posterior distribution of θ. Appreciation of the inferential contents of π(θ |z) may be enhanced by providing both point and region estimates of the vector of interest θ, and by declaring whether or not some context suggested specific value θ0 is compatible with the observed data z (precise hypothesis testing). A large number of Bayesian estimation and hypothesis testing procedures have been proposed in the literature. We argue that their choice is better made in decision theoretical terms.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Bayesian Frequentist Multiple Testing

We introduce a Bayesian approach to multiple testing. The method is an extension of the false discovery rate (FDR) method due to Benjamini and Hochberg (1995). We also examine the empirical Bayes approach to simultaneous inference proposed by Efron, Tibshirani, Storey and Tusher (2001). We show that, in contrast to the single hypothesis case – where Bayes and frequentist tests do not agree even...

متن کامل

Bayesian and Frequentist Multiple Testing

We introduce a Bayesian approach to multiple testing. The method is an extension of the false discovery rate (FDR) method due to Benjamini and Hochberg (1995). We also examine the empirical Bayes approach to simultaneous inference proposed by Efron, Tibshirani, Storey and Tusher (2001). We show that, in contrast to the single hypothesis case – where Bayes and frequentist tests do not agree even...

متن کامل

Parametric Empirical Bayes Test and Its Application to Selection of Wavelet Threshold

In this article, we propose a new method for selecting level dependent threshold in wavelet shrinkage using the empirical Bayes framework. We employ both Bayesian and frequentist testing hypothesis instead of point estimation method. The best test yields the best prior and hence the more appropriate wavelet thresholds. The standard model functions are used to illustrate the performance of the p...

متن کامل

Similarity Analysis between Transcription Factor Binding Sites by Bayesian Hypothesis Test

Transcription factor binding sites (TFBS) in promoter sequences of higher eukaryotes are commonly modeled using position frequency matrices (PFM). The ability to compare PFMs representing binding sites is especially important for de novo sequence motif discovery, where it is desirable to compare putative matrices to one another and to known matrices. We propose to identify and group similar pro...

متن کامل

On the use of non-local prior densities in Bayesian hypothesis tests

We examine philosophical problems and sampling deficiencies that are associated with current Bayesian hypothesis testing methodology, paying particular attention to objective Bayes methodology. Because the prior densities that are used to define alternative hypotheses in many Bayesian tests assign non-negligible probability to regions of the parameter space that are consistent with null hypothe...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2011